Neuropsychological deficits in chronic fatigue syndrome: artifact or reality?

Chronic fatigue syndrome is an illness characterised by extreme fatigue of uncertain origin which has been present for at least six months. The fatigue should have a sudden onset and be severe enough to substantially reduce the patient’s day to day activities. A number of other symptoms are associated with chronic fatigue syndrome including complaints of impaired memory, difficulty making decisions, poor attention, and reduced concentration. Many patients complain that it is these cognitive symptoms which cause them the greatest frustration and disability.

You can read the rest of this article here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC486357/pdf/jnnpsyc00017-0004.pdf

 

Source: Moss-Morris R, Petrie KJ, Large RG, Kydd RR. Neuropsychological deficits in chronic fatigue syndrome: artifact or reality? J Neurol Neurosurg Psychiatry. 1996 May;60(5):474-7. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC486357/

 

Cognitive functioning in chronic fatigue syndrome and depression: a preliminary comparison

Abstract:

This study used a brief battery of neuropsychological measures to examine the performance of patients with chronic fatigue syndrome (CFS) (N = 16) and patients in a major depressive episode (N = 23). The overall neuropsychological performance of the CFS group was not significantly different from depressed patients, and both groups scored within normal limits on most measures. Variability of neuropsychologic performance was in general unrelated to level of depressive symptoms. The results are discussed in terms of the validity of the cognitive criterion for the CFS diagnosis. Subjective complaints of cognitive dysfunction by CFS patients in light of the lack of objective evidence for the same are considered in terms of a somatic vigilance hypothesis.

 

Source: Schmaling KB, DiClementi JD, Cullum CM, Jones JF. Cognitive functioning in chronic fatigue syndrome and depression: a preliminary comparison. Psychosom Med. 1994 Sep-Oct;56(5):383-8. http://www.ncbi.nlm.nih.gov/pubmed/7809336