Abstract:
OBJECTIVE: The hypothesized polysomnographic marker for depression, Rapid Eye Movement Latency (REML), was used to investigate two groups of subjects; Chronic Fatigue Syndrome (CFS)-not depressed and CFS-depressed.
METHOD: CFS subjects were classified into depressed and not depressed groups, using the Diagnostic Interview Schedule (DIS), and subsequently were studied in a sleep laboratory to ascertain REML.
RESULTS: Short REML showed a statistically significant correlation with the depressed state in CFS subjects.
CONCLUSION: Short REM latency is associated with depression in the CFS population.
Source: Morehouse RL, Flanigan M, MacDonald DD, Braha D, Shapiro C. Depression and short REM latency in subjects with chronic fatigue syndrome. Psychosom Med. 1998 May-Jun;60(3):347-51. http://www.ncbi.nlm.nih.gov/pubmed/9625223