Neuroendocrine and immune contributors to fatigue
Abstract: Central fatigue, a persistent and subjective sense of tiredness, generally correlates poorly with traditional markers of disease. It is …
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What is fatigue? Pathological and nonpathological fatigue
Abstract: Aid in understanding issues surrounding the construct validity of fatigue including the distinction between pathological versus nonpathological fatigue. Fatigue …
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XMRV: does this virus hold the key to myalgic encephalomyelitis/CFS?
Abstract: In October 2009 a team of researchers from the Whittemore Peterson Institute, in association with the National Cancer Institute …
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TLR3 agonists as immunotherapeutic agents
The interaction of innate and adaptive immune responses is extremely complex and just beginning to be understood in detail. The …
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Measuring fatigue in clinical and community settings
Abstract: OBJECTIVE: The Chalder Fatigue Scale (CFQ) is a widely used instrument to assess fatigue in both clinical and nonclinical …
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Treatment of the narcoleptiform sleep disorder in chronic fatigue syndrome and fibromyalgia with sodium oxybate
Abstract: This study investigates the response of the underlying sleep disorder associated with Chronic Fatigue Syndrome (CFS) and fibromyalgia (FM) …
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Measuring substantial reductions in functioning in patients with chronic fatigue syndrome
Abstract: PURPOSE: All the major current case definitions for chronic fatigue syndrome (CFS) specify substantial reductions in previous levels of …
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Relationships among rhinitis, fibromyalgia, and chronic fatigue
Abstract: New information about the pathophysiology of idiopathic nonallergic rhinopathy indicates a high prevalence in chronic fatigue syndrome (CFS). This article shows …
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Illness trajectories in the chronic fatigue syndrome: a longitudinal study of improvers versus non-improvers
Abstract: The natural progression of chronic fatigue syndrome (CFS) in adults is not well established. The aims of this longitudinal study were …
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An intriguing and hitherto unexplained co-occurrence: Depression and chronic fatigue syndrome are manifestations of shared inflammatory, oxidative and nitrosative (IO&NS) pathways
Abstract: There is a significant ‘comorbidity’ between depression and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Depressive symptoms frequently occur during the course …
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