TREATMENT DATABASE

NADH is the reduced form of nicotinamide adenine dinucleotide (NAD), also called ubiquinone reductase. It is found in all living cells.When NAD is oxidized (NAD+) in the cell's mitochondria, energy is released. This energy is preserved in the form of adenosine triphosphate (ATP), a substance required by all energy-absorbing processes in the body.

A growing body of research has documented that NADH not only acts as a driving force in the production of cellular energy, but also is a potent antioxidant, is a key component of DNA repair and cellular regeneration, and stimulates the production of the neurotransmitters dopamine, noradrenaline, and serotonin. Ongoing research in the United States and abroad may help define the role of NADH in treating such degenerative neurological conditions as Alzheimer's disease and Parkinson's disease.

USES IN ME/CFS: Researchers have proposed that NADH may help correct the metabolic defect in ME/CFS that inhibits the production of ATP. Because low ATP production means less energy, clinicians believe NADH may alleviate exhaustion and may also improve cognitive function. The three neurotransmitters stimulated by NADH serve critical functions in the central nervous system: dopamine is important for short-term memory; noradrenaline contributes to alertness; and serotonin has a pronounced effect on mood and regulates sleep.

Treatment rating for NADH (ENADA)