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CAUTION: Do not take Cytotec during pregnancy.

Cytotec (misoprostol) is a synthetic prostaglandin analogue that replaces depleted gastric prostaglandins. It is routinely used to prevent gastric ulcers in elderly or debilitated patients who are receiving nonsteroidal anti-inflammatory drug (NSAID) therapy. In these patients, the actions of natural prostaglandins (hormone-like substances that regulate inflammation, blood vessel dilation, and a host of other physiological responses) are blocked.

USES IN ME/CFS: Cytotec is primarily recommended for patients who are taking non-steroidal anti-inflammatory drugs (NSAIDs). Cytotec not only protects the stomach lining from the damaging effects of pain killers, it also appears to protect the small intestines. Dr. Leo Galland believes the drug can prevent “leaky gut,” a condition in which the small intestine becomes overly permeable, thereby leading to food sensitivities and allergies. Cytotec is also used to treat Interstitial Cystitis (IC), a condition experienced by many people with ME/CFS. In 1998 Kelly et al found that 24 out of 25 patients with IC improved after receiving misoprostol, with minimal side effects.


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