TREATMENT DATABASE

Cardene (nicardipine) is a calcium channel blocker. Calcium channel blockers work by preventing calcium ions from entering smooth muscle cells. Calcium is especially important for the functioning of these cells and specialized cells in the heart. When calcium levels are lowered, the result is a relaxation of blood vessels, allowing an increased supply of blood and oxygen to the heart while decreasing its work load. As a consequence of their effect on blood vessels, calcium channel blockers are useful in treating cardiovascular disorders, such as angina (chest pain) and coronary artery disease, and to lower blood pressure. These drugs also may improve exercise capacity and subsequently reduce the need for surgery in patients with cardiac problems.

USES IN ME/CFS: After treatment with calcium channel blockers, Dr. Ismael Mena reported that some of his patients exhibited clinically improved cerebral blood flow (CFIDS Chronicle, Spring/Summer 1990).

A number of ME/CFS clinicians have noted improvement in cognitive function in patients given calcium channel blockers. Cardene also is helpful in treating migraine-type headaches. Dr. Jay Goldstein also observed improvements in cognitive function and energy level in patients given calcium channel blockers. 

Treatment rating for Cardene (nicardipine)