TREATMENT DATABASE
Valtrex (valacyclovir) is an oral pro-drug that converts to acyclovir once ingested. It is more bioavailable than acyclovir and is therefore more effective.
Valtrex is marketed for herpes simplex, but in 2009 Hoshino et al found that it also reduced the replication of EBV. They concluded that latent EBV (Epstein-Barr virus) might be completely eradicated by Valtrex if reinfection did not occur.
USES IN ME/CFS: A 2007 study by Dr. Lerner of ME/CFS patients with EBV reactivation found that Valtrex resulted in both increased physical functioning and improved heart functioning (reduced sinus tachycardia, decreased abnormal cardiac wall movements) as well as reducing EBV antibody levels. By the end of the 36-month trial many patients were able to resume normal activities.
| Rating | Side Effects | Reason for Treatment | Dosage / Duration | Age | Sex M/F | # of years Ill | Additional Comments | Illness Severity | Date Added |
|---|---|---|---|---|---|---|---|---|---|
| 5 | none | I take it daily and plan on doing for life. Helps with energy levels. | 9 month 1000 mg 1X day | 54 | Female | 30 | if my script runs out I start feeling much worse until I get a new script | Mild | 09/13/19 |
| 2 | No side effects but it hasn’t helped me at all! | Was hoping to get relief and feel better | 6 month 1,000 2X day | 39 | Female | 3 | I will continue it another 6 months to see if it helps at all | Moderate | 10/13/19 |