TREATMENT DATABASE



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Cymbalta is a serotonin-norepinephrine reuptake inhibitor (SNRI) primarily prescribed for pain. It is one of three medications currently approved for the treatment of fibromyalgia.

USES IN ME/CFS: Although Cymbalta is often prescribed by rheumatologists for their patients with fibromyalgia, most ME/CFS doctors prefer tricyclics or SSRIs over Cymbalta.

WARNING: Withdrawal symptoms after discontinuation can be severe.

Treatment rating for Cymbalta (duloxetine)

Rating keys:

1=LOW (I would not recommend this treatment)

5=HIGH (This treatment helped me a great deal)

Rating Side Effects Reason for Treatment Dosage / Duration Age Sex M/F # of years Ill Additional Comments Illness Severity Date Added
4 None I was only getting 2 - 4 hours of sleep a night -- never more than 4 hours -- for over a year. Cymbalta got me back to 8 hours of sleep a night. 5 year 30 mg 1X day 64 Female 41 It alleviated my depression. Moderate 04/07/23