TREATMENT DATABASE



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Sertraline (Zoloft) is an SSRI antidepressant that is similar to Prozac, but because it is associated with fewer side effects may be more easily tolerated. It has a shorter half-life than Prozac.

USES IN ME/CFS: Zoloft has been used to treat symptoms such as fatigue, cognitive dysfunction, mood swings, pain, sleep disorders, and immune dysfunction.As with other SSRIs, patient experiences vary widely. Some patients report an increase in energy and relief from pain, while others report nausea, loss of appetite, a “floating feeling,” and hormonal complications.

Withdrawal symptoms of paroxetine may be intense, producing flu-like symptoms, nausea, irritability, anxiety, and crying jags. A few patients have mentioned that they felt as bad while taking these drugs as they did with other antidepressants, reminding us that many patients cannot tolerate any form of antidepressant. For these patients, alternative treatments have been suggested, including vitamins, amino acids, herbs, and other complementary therapies.


Treatment rating for Zoloft (sertraline)

Rating keys:

1=LOW (I would not recommend this treatment)

5=HIGH (This treatment helped me a great deal)

Rating Side Effects Reason for Treatment Dosage / Duration Age Sex M/F # of years Ill Additional Comments Illness Severity Date Added
4 None To give a small boost to energy and wellbeing. 20 year 100 mg 1X day 67 Male 26 It is addictive and there are symptoms when trying to stop the drug. Moderate/Severe 09/14/19
5 None Depression 2 year 100 mg 1X day 39 Female 3 Works GREAT for me!!! I had tried several before and this one works the best for me. Moderate/Severe 10/13/19