TREATMENT DATABASE
Zyrtec (cetirizine) is a second-generation antihistamine that crosses the blood-brain barrier minimally, thereby reducing its sedating effects. Unlike other antihistamines, Zyrtec is only taken once a day, preferably at the same time.
USES IN ME/CFS: Paradoxically, Zyrtec D's (decongestant) stimulating effect may help insomnia. One patient reported that after suffering from frequent panic micro-arousals on a nightly basis, taking Zyrtec D actually helped her stay asleep. The Zyrtec elevated her metabolic rate, preventing the sudden release of adrenaline that was preventing her from getting into a deep sleep.
| Rating | Side Effects | Reason for Treatment | Dosage / Duration | Age | Sex M/F | # of years Ill | Additional Comments | Illness Severity | Date Added |
|---|---|---|---|---|---|---|---|---|---|
| 3 | None | Mast Cell Activation Syndrome was diagnosed by an ME/CFS expert. He put me on a H1 and H2 blocker protocol which included Zantac twice daily, Claritin in the morning and Zyrtec at night. | 3 year 10mg 1X day | 53 | Male | 4 | I didn’t benefit from the MCAS protocol after six months so stopped it. I stayed on Zyrtec to help with environmental allergens. | Moderate/Severe | 06/20/18 |