TREATMENT DATABASE

Quercetin, a flavonol, is chiefly used to treat asthma and allergies. Quercetin has properties similar to the antihistamine disodium cromoglycate (found in Gastrocrom and Nasalcrom). It can inhibit mast cell production and block histamine release, two functions that together can curb many allergic responses. In its antioxidant function, quercetin decreases the synthesis of pro-inflammatory leukotrienes, and inhibits free radical production and lipid peroxidation.

Quercetin is reported to help relieve muscle pain, particularly along the upper back and shoulders. It is commonly found in many food sources: green tea, apples, red onions, red grapes, citrus fruits, tomato, broccoli, leafy green vegetables, cranberries and raspberries, among others.

USES IN ME/CFS: An interesting study conducted in 2009 by Davis et al found that quercetin increased the genesis of mitochondria in mice, significantly improving exercise tolerance. The reason this study is important is that it was done in vivo. (Most studies on antioxidants are performed in test tubes.) As exercise intolerance is the hallmark symptom of ME/CFS, quercetin may play an important role in improving physical stamina among people with ME/CFS.

PROTOCOL. Because it is so poorly absorbed, quercetin needs to be taken with bromelain, an enzyme found in pineapple.

Treatment rating for Quercetin