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Goldenseal (Hydrastis canadensis) is a North American herb known best for its antibiotic properties. Berberine, a substance found in goldenseal, kills many of the bacteria that cause diarrhea, as well as the protozoa that cause amoebic dysentery and giardiasis. It has been used against cholera bacteria and as a treatment for throat, sinus, and topical bacterial infections. Research has shown that goldenseal is also effective against some viral infections.

USES IN ME/CFS: Patients generally use goldenseal to treat sinusitis and canker sores. It should be used with caution, however. Excessive or lengthy (more than 10 days) treatment can lead to neurological disturbances and gastrointestinal upset. The safest way to take goldenseal is externally as a poultice or paste spread directly over the sinuses or other affected area. Goldenseal should not be used during pregnancy because it stimulates uterine contractions.


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