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Ginseng (Panax schinseng, aka Chinese or Korean ginseng) is an ancient tonic and stimulant. It has been shown to possess anti-inflammatory, anti-diabetic, and antioxidant properties. Ginseng is frequently described as an “adaptogen,” which means it can have normalizing metabolic effects, especially when homeostasis is disrupted.

USES IN ME/CFS: Although it possesses enormous therapeutic potential for common ailments, ginseng is usually not recommended to patients with severe ME/CFS. Ginseng stimulates the adrenal glands and can increase production of interferon. Because many patients with ME/CFS have excessive interferon production as well as endocrine abnormalities, panax ginseng may increase symptoms.

Siberian ginseng (Eleutherococcus senticoccus), although it belongs to a different genus, has similar medicinal qualities to panax ginseng. (Though interestingly, Siberian ginseng appears to have the opposite effect of reducing inflammatory responses.) Siberian ginseng, marketed as Eleutherococcus Senticosus, is less expensive than panax ginseng and is often found in herbal ginseng formulations. (Check the label if you are looking for pure panax ginseng.)

Ginseng should not be used with estrogens or corticosteroids because of possible additive effects. It may affect the blood glucose levels of patients with diabetes mellitus.


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