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Malic acid, an intermediate in the Krebs cycle, aids in the production of adenosine triphosphate (ATP). It is found primarily in apples and pears, as well as other fruits, and is used primarily as a flavor enhancer and to lend tartness to food products. Malic acid helps in the breakdown and utilization of fats and glucose in muscle tissue, even in low oxygen conditions, and plays an important role in the production of ATP.

USES IN ME/CFS: Because of the prominent role malic acid plays in the energy-producing Krebs cycle, a deficiency can lead to inadequate breakdown of glucose in muscle tissue, with resulting buildup of lactic acid and other toxins. Increased amounts of malic acid should relieve many of the symptoms associated with tissue acidosis (spasms, cramps, and burning pain). A number of physicians recommend malic acid combined with magnesium to treat fibromyalgia symptoms.


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