TREATMENT DATABASE

Inosine is a purine ribonucleoside (a nitrogen-containing compound combined with D-ribose). Isoprinosine (brand: Imunovir) is its pharmaceutical equivalent (now largely replaced by inosine).

Inosine is a naturally occurring chemical in the body which leads to the production of uric acid, a potent free radical scavenger. As a basic component of cells, uric acid is involved in a number of physiological processes including carbohydrate metabolism, insulin regulation, and protein synthesis. (Uric acid levels are low in all inflammatory diseases.) Pharmaceutical forms of inosine (inosine pranobex, or isoprinosine) have been used as immune system modulators. Currently, inosine is being investigated as a possible treatment for Parkinson's disease.

As a supplement, inosine is primarily used to enhance athletic performance. Manufacturers claim that because inosine is a precursor to adenosine, it facilitates the production of ATP (adenosine triphosphate). As a consequence, inosine should theoretically increase energy and endurance. Although there does not appear to be any research to substantiate these claims, inosine is included in many sports supplements.

USES IN ME/CFS: Inosine, like its pharmaceutical counterpart, is supposed to modulate the immune system and act as an antiviral. However, inosine does not appear to possess the same antiviral properties as isoprinosine. The main function of inosine is as an antioxidant, which is linked to its ability to raise uric acid levels in the blood.

Treatment rating for Inosine