TREATMENT DATABASE

Amantadine (Symmetrel) is prescribed for viral infections (type A influenza virus) and Parkinson's disease. It acts by blocking the penetration of cell membranes by the infectious material from viruses. As an antiviral agent, it is of no benefit unless administered at the onset of infection.

USES IN ME/CFS: In patients who cannot tolerate flu shots, amantadine might be a good alternative, especially for those patients susceptible to frequent episodes of influenza. In ME/CFS, its most common use is not as an antiviral agent but as a stimulant. It is used to treat fatigue and lethargy in mild cases. Common side effects include insomnia, confusion, headaches, and dizziness. Amantadine interacts with antidepressants and antihistamines. Some patients cannot tolerate this drug so the initial dose should be small.

Treatment rating for Amantadine