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Glutamine is the most abundant nonessential amino acid in the body. It is a precursor to glutathione.

Glutamine plays an important role in many biological functions, including protein synthesis, providing cellular energy, and as a non-toxic transporter of ammonia in the bloodstream. When converted to glutamic acid, it acts as an excitatory neurotransmitter in the brain.

In the intestinal tract, glutamine strengthens the gut's function as an immune barrier by supporting the production of secretory immunoglobulin A (sIgA), which helps maintain the structure, metabolism, and function of the mucosal lining of the intestines. Glutamine can help heal injured gut mucosa after surgery and, in a high percentage (92%) of patients, completely heals ulcer damage. Glutamine is an important detoxifying agent for ammonia, a neurotoxin and one of the toxic by-products of protein metabolism. It is used to treat sugar craving, fatigue, ADHD, peptic ulcers, and personality disorders. Dietary sources of glutamine include beef, chicken, fish, eggs, milk, dairy products, wheat, cabbage, beets, beans, and spinach.

USES IN ME/CFS: Because it is so important in gastrointestinal growth and function, glutamine is primarily used to treat leaky gut. 

Some patients have noted improvement in gut function and increased food tolerance with this treatment as well as a decrease in “brain fog.” 


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