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Grape seed extract is a polyphenolic compound derived from grape seeds.

Grape seeds contain polyphenols, procyanidins, and proanthocyanidins, which are antioxidants many times more powerful than vitamin C or E. Grape seed extract is reported to be a potent peroxynitrite scavenger, and therefore can protect the cells from intracellular damage. The effects of polyphenols are far-reaching, including the inhibition of skin cancer, reduction of inflammation, neuroprotective action, improvement of cerebral circulation, acceleration of wound healing, modulation of intestinal flora, repairing leaky gut, and immune system regulation.

USES IN ME/CFS: Grape seed extract is often used as a less expensive alternative to pycnogenol. Patients report that it helps with pain.


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